Mississippi Science FB.4

ScienceGrades 9–12Foundations of Biology

Standard Cluster

Students will demonstrate an understanding of how genetic information is transferred from parent to offspring. Compare and contrast the basic structure and function of nucleic acids (e.g., DNA, RNA). Obtain and communicate information illustrating the relationships among DNA, genes, chromosomes, and proteins to the basis of life. Use models (e.g., Punnett squares) and mathematical reasoning to describe and predict patterns of inheritance of single genetic traits from parents to offspring (e.g., dominant, and recessive traits, incomplete dominance, codominance, multiple alleles, sex- linkage). Obtain and communicate information to describe how mutations may affect genetic expression and provide examples. Research and report on genetic technologies that may improve the quality of life (e.g., genetic engineering, cloning, gene splicing, DNA testing). Enrichment: Debate the pros and cons of using biotechnology to manipulate genetic information for human purposes (society).

2026 Mississippi College- and Career-Readiness Standards for Science · Molecular Basis of Heredity

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FB.4 is a cluster heading. These are the individual standards under it.

Teacher's field guide

What This Cluster Means

What Students Need to Do

Students compare DNA and RNA and trace how genes on chromosomes provide instructions for proteins. They use Punnett squares to predict how traits pass from parents to offspring. They explain possible effects of mutations and report on a genetic technology.

What Mastery Looks Like

A student can tell DNA from RNA and explain how a gene relates to a protein. They can calculate offspring probabilities for dominant, recessive, incomplete dominance, codominance, multiple-allele, and sex-linked traits. They can explain why a mutation may change a protein or have no effect, then weigh evidence about a genetic technology.

Common Misconceptions

Students may treat genes, chromosomes, and proteins as the same thing. They may think dominant means common, or that a 25% chance guarantees exactly one affected child in every four. They may assume every mutation is harmful and every positive genetic test guarantees disease.

How to Assess It

Exit ticket: Two parents are Aa for a recessive condition. Draw a Punnett square, give the chance of an affected child, and explain how a DNA change could alter the related protein.

Lesson moves

Ways to Teach It

  1. Build a DNA gene with colored paper bases, transcribe an RNA strand, and use a codon chart to identify the resulting amino acids.

  2. Ask: If one DNA base changes, must the protein change? Have students use a codon chart to defend their answers.

  3. Give pairs parent genotype cards for ABO blood type; have them draw Punnett squares and compare offspring probabilities.

  4. Hand out two short articles on sickle cell gene therapy; have students report one benefit, one risk, and one limitation.

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Printable FB.4 Worksheet

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