Mississippi Science GEN.1A.6

ScienceGrades 9–12Genetics

The Standard

GEN.1A
Students will demonstrate that all cells contain genetic material in the form of DNA.
Investigate the structural differences between the genomes (i.e., circular/linear chromosomes and plasmids) found in prokaryotes and eukaryotes.

2026 Mississippi College- and Career-Readiness Standards for Science · Structure and Function of DNA

Teacher's field guide

What This Standard Means

What Students Need to Do

Students compare how DNA is arranged in prokaryotic and eukaryotic cells. They tell a main chromosome from a plasmid and show the difference in a sketch.

What Mastery Looks Like

A student can draw a typical bacterium with one circular chromosome and a separate, smaller plasmid. They can draw a eukaryotic nucleus with several linear chromosomes and explain what the shapes show.

Common Misconceptions

Students may call every circular DNA molecule a plasmid or think a plasmid replaces the main chromosome. They may think every prokaryote has plasmids or that all cells keep chromosomes in a nucleus.

How to Assess It

Ask students to draw the DNA in a typical bacterium and an animal cell. Have them label the chromosomes and add a possible plasmid to the bacterium.

Lesson moves

Ways to Teach It

  1. Give pairs one long yarn loop, two short loops, and three yarn strips; have them model bacterial and animal DNA and label each part.

  2. Ask, "If a bacterium has two DNA loops, why might only one be called its chromosome?" Have students write two sentences.

  3. Hand out cards showing a bacterial chromosome, a bacterial plasmid, and a human chromosome; students sort them by shape, size, and cell type.

  4. Show a sketch of an antibiotic resistance plasmid beside a bacterial chromosome; students circle the plasmid and explain the difference.

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Printable GEN.1A.6 Worksheet

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