Mississippi Science HAP.4.5

ScienceGrades 9–12Human Anatomy and Physiology

The Standard

HAP.4
Students will investigate the structures and functions of the skeletal system including the cause and effect of diseases and disorders.
Construct explanations detailing how mechanisms (e.g., Ca2+ regulation) are used by the skeletal system to maintain homeostasis.

2026 Mississippi College- and Career-Readiness Standards for Science · Skeletal System

Teacher's field guide

What This Standard Means

What Students Need to Do

Explain how bones store calcium while the body keeps blood calcium within a narrow range. Trace how parathyroid hormone increases calcium release from bone when blood levels fall. Show how rising blood calcium slows that response.

What Mastery Looks Like

Given a low blood calcium reading, students predict more parathyroid hormone and more calcium release from bone. They can explain why hormone levels fall as blood calcium recovers.

Common Misconceptions

Students may think calcium is only for building bones, not for muscle and nerve function. Some reverse the feedback loop and say low blood calcium lowers parathyroid hormone.

How to Assess It

Exit ticket: Blood calcium drops. Draw arrows showing what happens next to parathyroid hormone, calcium release from bone, and blood calcium. What slows the response?

Lesson moves

Ways to Teach It

  1. Give pairs cups labeled bone and blood, plus 12 beans; have them move beans after drawing a low blood calcium card.

  2. Ask partners to challenge the claim, 'Bones only provide support,' using blood calcium and a feedback arrow.

  3. Give teams cards labeled low blood calcium, increased parathyroid hormone, bone calcium release, and restored blood calcium to arrange in order.

  4. Show a mock chart with low calcium intake, normal blood calcium, and declining bone density; ask students to explain the pattern.

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Printable HAP.4.5 Worksheet

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A ready-to-print activity worksheet aligned to HAP.4.5, with an answer key for the teacher on its own page. No account needed.

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