Mississippi Science HAP.11.5
The Standard
- HAP.11
- Students will investigate the structures and functions of the lymphatic system, including the cause and effect of diseases and disorders.
Differentiate the role of B-lymphocytes and T-lymphocytes in the development of humoral and cell-mediated immunity and primary and secondary immune responses.
2026 Mississippi College- and Career-Readiness Standards for Science · Lymphatic System
Teacher's field guide
What This Standard Means
What Students Need to Do
- Students explain how B cells become antibody-producing plasma cells and how helper and cytotoxic T cells respond to infection. They compare the body's first encounter with an antigen to a later encounter with the same antigen.
What Mastery Looks Like
- Given a virus entering the body twice, a student can identify antibodies as part of the B-cell response and infected-cell killing as a cytotoxic T-cell response. They can explain why memory B and T cells make the second response faster.
Common Misconceptions
- Students may say T cells make antibodies or that B cells kill infected cells directly. They may call any new infection a secondary response, even when it involves a different antigen.
How to Assess It
- Exit ticket: A virus enters the body for the first time, then returns months later. What do B cells and cytotoxic T cells do, and why is the second response faster?
Lesson moves
Ways to Teach It
Give pairs B-cell, helper T-cell, cytotoxic T-cell, antibody, and memory-cell cards to place on a first-exposure and repeat-exposure timeline.
Have students write two sentences comparing how antibodies act on free virus particles and how cytotoxic T cells act on infected cells.
Play a card match with B cell, antibody, cytotoxic T cell, infected cell, and memory cell, requiring an explanation for each match.
Show a two-dose vaccine schedule for the same antigen and have students label the first response, memory-cell formation, and booster response.
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Printable HAP.11.5 Worksheet
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Related Standards
- HAP.9.2
Distinguish the cellular difference between the ABO blood groups and investigate blood type differences utilizing antibodies to determine compatible donors and ...
- HAP.11.1
Analyze the functions of leukocytes, lymph, and lymphatic organs in the immune system.
- HAP.11.3
Compare and contrast the body’s non-specific and specific lines of defense, including an analysis of the roles of various leukocytes: basophils, eosinophils, ne...
- HAP.11.4
Correlate the functions of the spleen, thymus, lymph nodes, and lymphocytes to the development of immunity.
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