Mississippi Science HAP.5.3

ScienceGrades 9–12Human Anatomy and Physiology

The Standard

HAP.5
Students will investigate the structures and functions of the muscular system, including the cause and effect of diseases and disorders.
Explain the molecular mechanism of muscle contraction and relaxation.

2026 Mississippi College- and Career-Readiness Standards for Science · Muscular System

Teacher's field guide

What This Standard Means

What Students Need to Do

Trace how a nerve signal releases calcium and exposes binding sites on actin. Explain how myosin pulls actin, how ATP lets myosin detach and reset, and how calcium removal allows relaxation.

What Mastery Looks Like

A student can put calcium release, myosin binding, pulling, ATP-driven detachment, and calcium reuptake in order. They can explain why the filaments slide past each other rather than shorten.

Common Misconceptions

Students may think actin and myosin get shorter when a muscle contracts. They may also think ATP is only needed for contraction, or that calcium pulls the filaments.

How to Assess It

On an exit ticket, have students order calcium release, myosin binding, pulling, ATP-driven detachment, and calcium reuptake. Ask them to explain what makes the muscle relax.

Lesson moves

Ways to Teach It

  1. Use yarn for actin, paper clips for myosin, and labeled calcium and ATP slips to model pulling, detachment, and relaxation.

  2. Ask pairs why pumping calcium back into storage stops myosin from grabbing actin, even while ATP is available.

  3. Give groups shuffled contraction event cards and have them race to sequence the cards, then explain each step.

  4. Write 'A body becomes stiff after death' on the board, then ask students to connect rigor mortis to ATP and myosin detachment.

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Printable HAP.5.3 Worksheet

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