Mississippi Science GEN.2B.5
The Standard
- GEN.2B
- Students will determine the causes and effects of mutations in DNA.
Enrichment: Use an engineering design process to research the current status of genetic technology and personalized medicine, then propose and test targeted medical or forensic applications. *
2026 Mississippi College- and Career-Readiness Standards for Science · Transcription, Translation, and Mutations
Teacher's field guide
What This Standard Means
What Students Need to Do
- Students check a dated FDA or NIH source to learn what a genetic technology can do now. They set accuracy and privacy requirements, propose a targeted medical or forensic use, and test a paper model with mock cases.
What Mastery Looks Like
- A student names the genetic marker their design uses and cites a dated source about the technology. They test their rule on new cases, record wrong or unclear calls, and revise it.
Common Misconceptions
- Students may treat one variant as a guarantee of disease or treatment success. They may treat an unclear result as a negative result or overlook consent and privacy.
How to Assess It
- Give students a current FDA label for a biomarker-guided drug and mock test cards marked positive, negative, and unclear. Ask them to write a screening rule, apply it to each card, and explain why the rule cannot choose treatment alone.
Lesson moves
Ways to Teach It
Pairs use fictional Drug X cards with variants on the front and outcomes on the back to test and revise a screening rule.
Ask: What does a dated FDA page say this genetic test can show, and what information would a doctor still need?
Run a design-review game: teams draw mock cases with missing results and earn points for flagging uncertain calls instead of guessing.
Open an FDA label for a biomarker-guided drug; find its testing requirement and compare it with the class Drug X rule.
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